使代谢组学在发现中药毒性物质、揭示毒性机制（生物标志物）方面发挥作用
崔立然
代谢组学技术在中药毒性研究中的应用前景[EB/OL]
北京：中国科技论文在线
其全景式、整体互动性的特点与中医药的整体观念、证候的复杂体系及动态连贯性、中药作用的多靶点和突出整体效应不谋而合
对中药毒性研究的科学化、规范化、现代化和国际化具有重要的促进作用和学术意义
是中药毒性研究的最佳切入点
代谢组学
） Abstract： It has many merits which may retain the internal environment not be destroyed and possess the integrity and the high sensitivity in the metabonomics
Metabonomics is the best point for us to study the toxicity research of Cmm（Chinese material medica）because it has the feature of panorama type and whole interaction
The feature of metabonomics is coincidence with the viewpoints of the theory of traditional Chinese medicine, which are entirety viewpoint , complicated symptoms system , dynamic state coherent , multitarget of Cmm and emphasizing the effect of integrity
Followed by the theory of Metabonomics Technology will help Cmm to find New toxical substances and to find out their toxicalmechanism(biomarker)
The Study of toxicology of Cmm will be more scientific and canonical and then Improve Cmm to realize modernization and internationalization by combining theory of Cmm with molecular biological technology system is tightly
Keywords： toxicity of Chinese material medica;metabonomics;whole interaction;biomarker 下载PDF阅读器 PDF全文下载： 初稿 （ 601 ） 作者简介： 通信联系人： 【收录情况】 中国科技论文在线： 刘树民
整体互动性
） 摘要： 代谢组学具有不破坏内环境、整体性、灵敏度高的特点
