） Abstract： Organotin derivatives as well as pyrazole and their derivatives play crucial roles as the active moieties in varieties of agrochemicals
Along with the increasing interest in use of sulfur- or nitrogen-functionalized carboxylic acids to yield organotin carboxylates with various and fascinating structures and different bioactivities, these features encourage the exploitation of the biological activity of organotin carboxylates containing pyrazole
In this paper, a series of organotin 1-phenyl-3,5- dimethylpyrazole-4-carboxylates and 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylates have been obtained and characterized by IR, NMR (1H, 13C and 119Sn) and elemental analysis
The structure of triethyltin 1-phenyl-3,5-dimethylpyrazole-4-carboxylate has been further confirmed by X-ray diffraction crystallography
This complex crystallizes with a molecule of water and forms an infinite 2D network through intermolecular O-H…O and O-H…N hydrogen bonds
Fungicide screening indicates that all complexes display good growth inhibition against Alternaria solani, Cercospora arachidicola, Gibberella zeae, Physalospora piricola and Botrytis cinerea
Moreover, high growth inhibition percentage at 50 μg/ml was observed in vitro in case of triorganotin 1-phenyl-3,5-dimethylpyrazole-4-carboxylates and 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylates
The corresponding EC50 of these highly active triorganotin carboxylates have been detected
The value of EC50 of triethyltin 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylate is only 0
06 μg/ml against Physalospora piricola and 0
14 μg/ml against Gibberella zeae, respectively
Keywords： organotin carboxylate; 1-aryl-3,5-dimethylpyrazole-4-carboxylic acid; crystal structure; fungicidal activity 下载PDF阅读器 PDF全文下载： 初稿 （ 189 ） 作者简介： Dr
Wang acquired her Ph
D
in chemistry at Texas A&M University and have been associate professor at Nankai University since then
Her research focuses on physical organic and organometallic chemistry
通信联系人： 【收录情况】 中国科技论文在线： 王志宏
） 摘要： Organotin derivatives as well as pyrazole and their derivatives play crucial roles as the active moieties in varieties of agrochemicals
Along with the increasing interest in use of sulfur- or nitrogen-functionalized carboxylic acids to yield organotin carboxylates with various and fascinating structures and different bioactivities, these features encourage the exploitation of the biological activity of organotin carboxylates containing pyrazole
In this paper, a series of organotin 1-phenyl-3,5- dimethylpyrazole-4-carboxylates and 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylates have been obtained and characterized by IR, NMR (1H, 13C and 119Sn) and elemental analysis
The structure of triethyltin 1-phenyl-3,5-dimethylpyrazole-4-carboxylate has been further confirmed by X-ray diffraction crystallography
This complex crystallizes with a molecule of water and forms an infinite 2D network through intermolecular O-H…O and O-H…N hydrogen bonds
Fungicide screening indicates that all complexes display good growth inhibition against Alternaria solani, Cercospora arachidicola, Gibberella zeae, Physalospora piricola and Botrytis cinerea
Moreover, high growth inhibition percentage at 50 μg/ml was observed in vitro in case of triorganotin 1-phenyl-3,5-dimethylpyrazole-4-carboxylates and 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylates
The corresponding EC50 of these highly active triorganotin carboxylates have been detected
The value of EC50 of triethyltin 1-(2-pyridyl)-3,5-dimethylpyrazole-4-carboxylate is only 0
06 μg/ml against Physalospora piricola and 0
14 μg/ml against Gibberella zeae, respectively
关键词： organotin carboxylate; 1-aryl-3,5-dimethylpyrazole-4-carboxylic acid; crystal structure; fungicidal activity WANG Zhihong *
王贺等
Synthesis, structure and fungicidal activity of organotin 1-aryl-3,5-dimethylpyrazole-4-carboxylates[EB/OL]
