环肽GG6F的合成[EB/OL]
北京:中国科技论文在线
以Wang树脂为固相载体
固相合成直链肽前体
) Abstract: In this paper, the first synthesis of GG6F is described
The linear peptide was obtained with initial amino acid Gly as the N-terminal, using Wang-resin as solid carrier, HATU/HOAt as condensing agent and N,N-dimethylformamide as solvent via solid phase synthesis
Peptide cyclisation was carried out in liquid phase
The structure of synthesized GG6F, cyclo-(Gly-Leu-Val-Leu-Leu-Phe), was identified by 1 H NMR, 13 C NMR and MS
Keywords: Cyclopeptide, Solid phase peptide synthesis, Wang-resin 下载PDF阅读器 PDF全文下载: 初稿 ( 21 ) 作者简介: 陈杰桃(1991-),女,硕士研究生,天然环肽的化学合成及其生物活性研究 通信联系人: 穆青(1964-),男,教授,主要研究方向:药用植物化学成分及其活性研究 【收录情况】 中国科技论文在线: 陈杰桃